Neutrophil to Lymphocyte Ratio (NLR), Complete Blood Count (CBC) With Differential and Platelet

Casandra

Casandra Test Code LC05117Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 005013CPT Code 85025

Neutrophil to Lymphocyte Ratio (NLR), Complete Blood Count (CBC) With Differential and Platelet

Also known as: CBC/D/Plt+NLR

Clinical Use

Order Test

Use

NLR (Neutrophil to Lymphocyte Ratio) is a biomarker that can be used as an indication of subclinical inflammation. NLR is a calculation based on the Absolute Neutrophil Count divided by the Absolute Lymphocyte Count determined by the peripheral blood CBC differential. This calculation, according to recent literature, is useful in assessing the likelihood of severe progression of disease in SARS-CoV-2 positive patients.

Special Instructions

Not provided.

Limitations

Turnaround time may vary and not all sites may perform the six-part differential. Elevated IG percentages alone aren't clinically significant as sole predictors but are associated with conditions such as infections, inflammatory disorders, and medications like steroids. Pregnancy may also alter results due to physiological changes.

Test Details

Methodology

Automated Analyzer (Hematology)

Biomarkers

Neutrophil to Lymphocyte Ratio

Analyte

Ratio

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Result Codes

6690-2 - WBC # Bld Auto
789-8 - RBC # Bld Auto
718-7 - Hgb Bld-mCnc
4544-3 - Hct VFr Bld Auto
787-2 - MCV RBC Auto
785-6 - MCH RBC Qn Auto
786-4 - MCHC RBC Auto-EntMCnc
788-0 - Erythrocyte DistWidth Bld Auto
777-3 - Platelet # Bld Auto
770-8 - Neutrophils NFr Bld Auto
736-9 - Lymphocytes NFr Bld Auto
5905-5 - Monocytes NFr Bld Auto
713-8 - Eosinophil NFr Bld Auto
706-2 - Basophils NFr Bld Auto
75652-8 - Imm Lymphs Bld Ql
751-8 - Neutrophils # Bld Auto
731-0 - Lymphocytes # Bld Auto
742-7 - Monocytes # Bld Auto
711-2 - Eosinophil # Bld Auto
704-7 - Basophils # Bld Auto
71695-1 - Imm Granulocytes NFr Bld Auto
53115-2 - Imm Granulocytes # Bld Auto
58413-6 - nRBC Bld Auto-Rto
18314-5 - Morphology Bld-Imp

Result Turnaround Time

1 day

Specimen

Whole Blood

Volume

Fill tube to capacity.

Minimum Volume

0.5 mL (500 μL for pediatric microtainer capillary tubes; fill tube to capacity)

Container

Lavender-top (EDTA) tube

Collection Instructions

Invert tube 8 to 10 times immediately after tube is filled at the time of collection.

Storage Instructions

Maintain specimen at room temperature.

Causes for Rejection

Hemolysis; clotted specimen; specimen drawn in any anticoagulant other than EDTA; specimen diluted or contaminated with IV fluid; tube not filled with minimum volume; improper labeling; transfer tubes with whole blood; specimen received with plasma removed