Polychlorinated Biphenyls (PCB) Congeners, Screen and Confirmation
Also known as: Aroclors
Use
The test screens and confirms the presence of polychlorinated biphenyls (PCBs) in human serum. PCBs are man-made organic chemicals known as chlorinated hydrocarbons. They have been used in a variety of industrial applications such as coolants, electrical equipment, hydraulic systems, and as additives in sealants and flame retardants due to their non-flammability, chemical stability, high boiling point, and electrical insulating properties. The test aids in assessing exposure to PCBs, which can lead to potential adverse health outcomes such as cancer, immune, reproductive, nervous, and endocrine system disruptions.
Special Instructions
Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube. Do not use gel-barrier tubes as these are a cause for rejection.
Limitations
The test is limited by its detection threshold; substances measured below 0.5 ng/mL may not be detected. Cross-reactivity with other substances may influence results. Further confirmatory tests might be required, impacting turnaround times. Samples older than three days need to be refrigerated or frozen to maintain integrity.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 73994-6
- 73994-6
- 73993-8
- 73992-0
- 74374-0
- 73991-2
- 74375-7
- 73990-4
- 73989-6
- 73988-8
- 73987-0
- 74376-5
- 12990-8
Result Turnaround Time
3-14 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
5 mL
Minimum Volume
1 mL
Container
Red-top tube (do not use gel-barrier tubes)
Collection Instructions
Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.
Storage Instructions
Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.
Causes for Rejection
Gel-barrier tubes