Renin Activity, Plasma, Three Specimens
Use
Renin Activity, Plasma, Three Specimens test is primarily used to evaluate the activity of renin in plasma. This measurement is critical in assessing renal function, managing hypertension, and evaluating various conditions related to fluid and electrolyte balance. Elevated or decreased renin activity can indicate issues like renovascular hypertension, primary hyperaldosteronism, and chronic kidney disease. The test provides valuable data in diagnosing and managing these conditions by helping healthcare providers understand the underlying physiological process driving the patient’s symptoms. This test is significant for tailoring medication and treatment strategies to achieve optimal patient outcomes.
Special Instructions
Not provided.
Limitations
The Renin Activity, Plasma test is subject to limitations inherent in its methodology and the physiological variability of the renin-angiotensin system, which can be influenced by factors such as posture, medications, diet, and time of day. Additionally, the interpretative value can be affected if the patient is not properly prepared or if the specimen handling does not adhere to the specified protocols. External factors like hemolysis or sample contamination can also affect results. The test requires precise timing for sample collection and administration of any therapeutic agents, necessitating strict adherence to the described procedure to ensure accurate results. The test has not been cleared or approved by the FDA, which may affect its acceptance in certain clinical settings.
Methodology
Other
Biomarkers
Renin Activity #1
AnalyteRenin Activity #2
AnalyteRenin Activity #3
Analyte
LOINC Codes
- 17515-8 - Renin BS Plas-cCnc
- 25513-3 - Renin sp1 p chal Plas-cCnc
- 12900-7 - Renin sp2 p chal Plas-cCnc
Result Turnaround Time
4-7 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
Not provided
Container
EDTA plasma specimen
Collection Instructions
Collect three specimens. Initial tube (baseline), followed by samples after administering treatment or glucola.
Storage Instructions
Keep the samples frozen for optimal analysis. Delay in freezing or improper handling may invalidate the test results.
Causes for Rejection
Rejection causes include non-frozen samples, non-separated samples, non-EDTA plasma specimens, and gross icterus.
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