Rubella Antibodies, IgM
Also known as: German Measles Specific IgM
Use
For the in vitro detection of IgM antibodies specific for rubella. IgM antibodies are associated with acute viral infections. IgM detection is useful in the following situations: evidence of infection can be obtained from only one acute phase specimen if the IgM results are positive; the IgM test can also be used to differentiate between primary infection and re-exposure. Rubella-specific IgM is found in virtually all infected patients by three weeks postdevelopment of a rash. Rubella-specific IgM is also found in 80% of postvaccination patients by three weeks. Congenitally infected infants will show an IgM response at 2 to 12 weeks postnatally.
Special Instructions
Not provided.
Limitations
The absence of IgM at birth does not rule out congenital rubella. IgM detection frequency decreases as conception and infection period extend. False positives may occur post-mononucleosis, parvovirus B19, or other herpes-type infections. Pregnant women may produce false positives, often accompanied by reactions to other viruses like CMV and measles.
Methodology
Immunoassay (CLIA)
Biomarkers
Rubella IgM Antibodies
Analyte
LOINC Codes
- 5335-5 - RUBV IgM Ser IA-aCnc
- 5335-5 - RUBV IgM Ser IA-aCnc
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.2 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Refrigerate. Stable for two days at room temp, seven days refrigerated. Freeze for longer storage.
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 2 days |
| Refrigerated | 7 days |
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