Salivary Cortisol (Three Specimens), MS (Endocrine Sciences)
Use
Salivary cortisol measurement is an important tool for assessing adrenal function and circadian rhythm disturbances. It is especially useful in diagnosing disorders such as Cushing's syndrome and Addison's disease. By measuring cortisol levels at three different time points, healthcare providers can evaluate the cortisol production profile, aiding in the diagnosis and management of endocrine disorders. This test is non-invasive and convenient, suitable for patients who need cortisol assessment throughout the day.
Special Instructions
The test is designed to measure cortisol levels from saliva specimens collected at three different time points. It is crucial to label each specimen tube with the patient's name, collection time, and date, and to submit all specimens on the same request form. Specialized kits are available for collection, and the specimens should be submitted simultaneously.
Limitations
The test is developed by LabCorp and has not been cleared or approved by the FDA. While it provides valuable insights into cortisol levels, results should be interpreted in conjunction with clinical findings and other diagnostic procedures. Variability in saliva collection methods or timing can affect results, and the stability of samples is influenced by environmental conditions during collection and storage. Freeze/thaw cycles may impact the accuracy of cortisol levels measured.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 51495-0
- 51494-3
- 51493-5
Result Turnaround Time
6-15 days
Related Documents
For more information, please review the documents below
Specimen
Saliva
Volume
1 mL (each specimen) per time point indicated
Minimum Volume
Not provided
Container
Salivette collection device
Collection Instructions
Label each tube with patient's name, collection time and date. Submit specimens simultaneously on the same request form.
Storage Instructions
Refrigerate.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 5 months |