Salivary Cortisol (Two Specimens), MS (Endocrine Sciences)
Use
The Salivary Cortisol test is valuable in assessing adrenal gland function, particularly in suspected cases of Cushing's syndrome, Addison's disease, and other disorders related to cortisol imbalance. Cortisol is a steroid hormone produced by the adrenal glands and plays a crucial role in various bodily functions, including metabolism, immune response, and stress response. This test measures the cortisol levels in saliva collected at two different time points, providing insight into the circadian rhythm of cortisol production, which is critical for diagnosing endocrine disorders.
Special Instructions
This test requires the collection of saliva at two specific time points. Each tube must be labeled with the patient's name, collection time, and date. Specimens should be submitted simultaneously on the same request form using the Salivette collection device. Specialized kits are available for salivary testing, and these can be ordered by contacting a local Labcorp representative.
Limitations
The accuracy of salivary cortisol tests can be affected by factors such as improper collection techniques, failure to collect at the designated time points, and potential contamination. This test is not FDA approved, and its performance characteristics are determined by LabCorp. Inter-individual variability in saliva production and factors such as medication, stress, or illness may also impact the results.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 54235-7
- 51495-0
- 51494-3
Result Turnaround Time
6-15 days
Related Documents
For more information, please review the documents below
Specimen
Saliva
Volume
1 mL (each specimen) per time point indicated
Minimum Volume
Not provided
Container
Salivette collection device
Collection Instructions
Label each tube with patient's name, collection time and date. Submit specimens simultaneously on the same request form.
Storage Instructions
Refrigerate.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 5 months |