Triiodothyronine (T3), Free, Dialysis and LC/MS-MS (Endocrine Sciences)
Also known as: Free T3, Free Triiodothyronine (T3), FT3
Use
Triiodothyronine (T3), Free, Dialysis and LC/MS-MS test is primarily used to provide a direct measurement of free tri-iodothyronine, a thyroid hormone, in the blood. This test is employed to assess thyroid function in various clinical scenarios, especially when normal protein binding may be altered, enhancing accuracy over automated methods. Conditions where this test is preferred include congenital thyroxine-binding protein deficiency, pregnancy, oral contraceptive or hormone therapy users, and those with critical illnesses. It helps in diagnosing hyperthyroidism, assessing thyroid function in patients with thyroid dysfunction, and monitoring patients on thyroid hormone replacement therapy.
Special Instructions
Serum or plasma should be separated from cells within 45 minutes of venipuncture. Ensure the serum/plasma is sent in a plastic transfer tube. Proper separation and handling of the specimen are crucial to avoid degradation or incorrect results.
Limitations
This test may not be suitable for patients whose samples cannot be prepared and analyzed quickly or handled correctly due to logistical issues. Furthermore, it may require additional confirmatory testing depending on clinical context. Results can be influenced by non-thyroidal illnesses due to altered protein levels or increased protein binding produced by various medications or clinical conditions.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 29239-1
- 29239-1
Result Turnaround Time
6-10 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube, gel-barrier tube, lavender-top (EDTA) tube, or green-top (sodium heparin) tube
Collection Instructions
Serum/plasma must be separated from cells within 45 minutes of venipuncture. Send serum/plasma in a plastic transfer tube.
Storage Instructions
Freeze (preferred) or refrigerate. Stable at room temperature or refrigerated for five days. Stable frozen for 70 days.
Causes for Rejection
Whole blood
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 5 days |
| Refrigerated | 5 days |
| Frozen | 70 days |
