Vancomycin, Serum, Trough
Also known as: Vancocin®
Use
Monitor therapeutic drug level
Special Instructions
Peak levels should be ordered using Test No. 070327. Trough levels should be ordered using Test No. 070328. Please label tubes appropriately as 'peak' and 'trough.'
Limitations
The use of gel-barrier tubes is not recommended due to the slow absorption of vancomycin by the gel, which could lead to decreased drug levels that may be clinically significant. High trough concentrations greater than 20 µg/mL are associated with nephrotoxicity.
Methodology
Immunoassay
Biomarkers
LOINC Codes
- 4092-3
- 4092-3
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube, lavender-top (K2- or K3- EDTA) tube, or green-top (heparin) tube. Do not use a gel-barrier tube.
Collection Instructions
Transfer separated serum or plasma to a plastic transport tube. Trough concentrations should be monitored. The trough sample is drawn immediately prior to the next dose.
Storage Instructions
Refrigerate
Causes for Rejection
Gel-barrier tube; hemolysis; lipemia; gross bacterial contamination
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 3 days |
| Refrigerated | 14 days |
| Frozen | 14 days |