Vectra®
Also known as: Vectra® DA Disease Activity Test
Use
Vectra® DA measures the concentration of 12 serum proteins. An algorithm is applied to these concentrations to calculate a quantitate disease activity score ranging from 1 to 100. Test results are intended to aid in the assessment of disease activity in RA patients when used in conjunction with standard clinical assessment. This test is not intended or validated to diagnose RA.
Special Instructions
The Vectra® test requires careful handling and timely processing of specimens. Allow the specimen to clot for 30 minutes before centrifugation, and separate it from cells within 45 minutes of draw. Proper storage and shipping conditions must be adhered to ensure specimen integrity. Samples must be shipped on frozen cool packs or dry ice to avoid degradation, and sufficient dry ice must be used to ensure samples remain frozen upon reception.
Limitations
The Vectra® Score is computed using the concentrations of specified biomarkers and is intended exclusively for assessing disease activity in RA patients. It does not replace clinical assessments nor should it be used interchangeably with results from different methodologies. Its accuracy can be influenced by patient-specific factors such as age, gender, and adiposity. Additionally, the test is not suitable for patients outside the specified age range (below 18 or above 100 years) and may not be FDA-cleared.
Methodology
Immunoassay (Multiplex Protein Panel)
Biomarkers
LOINC Codes
- 75635-3
- 75633-8
- 75634-6
- 75627-0
- 26881-3
- 75629-6
- 14049-1
- 75628-8
- 21365-2
- 75632-0
- 75630-4
- 75631-2
- 48663-9
- 1847-3
- 1988-5
Result Turnaround Time
6-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
Gel-barrier tube, red-top tube or serum transfer tube
Collection Instructions
Allow specimen to clot for 30 minutes. Centrifuge and separate from cells within 45 minutes of draw. Transfer to a plastic transport tube before shipping.
Storage Instructions
Ship on frozen cool packs or dry ice. Ship with enough dry ice so ice exists upon receipt of package. Samples cannot go above room temperature.
Causes for Rejection
Gross hemolysis; gross lipemia; improper labeling; patients less than 18 years old or more than 100 years old
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 3 days |
| Refrigerated | 14 days |
| Frozen | 326 days |