Vectra® with CV Risk
Also known as: Vectra® DA Disease Activity Test
Use
Vectra® DA measures the concentration of 12 serum proteins. An algorithm is applied to these concentrations to calculate a quantitate disease activity score ranging from 1 to 100. Test results are intended to aid in the assessment of disease activity in RA patients when used in conjunction with standard clinical assessment. This test is not intended or validated to diagnose RA.
Special Instructions
The Vectra Cardiovascular Risk is only intended for rheumatoid arthritis patients aged 40 and above with no prior history of heart attack or stroke. It is not intended for patients using anti-IL-6R treatment, patients with a diagnosis of cancer (excluding non-melanoma skin cancer), or patients that have been hospitalized within the past 14 days.
Limitations
The individual biomarker results are intended for use in the generation of the Vectra score only and should not be used interchangeably with results generated by different methodologies. Clinical interpretation of individual biomarker levels, which have different weights in the Vectra algorithm, has not been established. This test has not been cleared or approved by the Food and Drug Administration (FDA).
Methodology
Immunoassay (Multiplex Protein Panel)
Biomarkers
LOINC Codes
- 75635-3
- 75633-8
- 75634-6
- 1847-3
- 1988-5
- 75627-0
- 26881-3
- 75629-6
- 14049-1
- 75628-8
- 21365-2
- 75632-0
- 75630-4
- 75631-2
- 48663-9
Result Turnaround Time
6-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
Gel-barrier tube, red-top tube or serum transfer tube
Collection Instructions
Allow specimen to clot for 30 minutes. Centrifuge and separate from cells within 45 minutes of draw. Transfer to a plastic transport tube before shipping.
Storage Instructions
Ship on frozen cool packs or dry ice. Ship with enough dry ice so ice exists upon receipt of package. Samples cannot go above room temperature.
Causes for Rejection
Gross hemolysis; gross lipemia; improper labeling; patients less than 18 years old or more than 100 years old
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 3 days |
| Refrigerated | 14 days |
| Frozen | 326 days |