VistaSeq® APC Comprehensive Analysis
Also known as: Familial Adenomatous Polyposis, Familial Cancer testing, Hereditary Cancer testing, Inherited Cancer testing
Use
This assay is intended for patients with a history consistent with Familial Adenomatous Polyposis.
Special Instructions
Not provided.
Limitations
Sequencing cannot detect variants in regions not covered by this analysis, including noncoding or deep intronic variants, and may not reliably detect changes in repetitive elements, such as microsatellite repeats. The test may miss mosaic variants, inversions, or other genomic rearrangements like transposable element insertions. Copy number analyses may not detect rearrangements such as translocations or some partial exon rearrangements. Pseudogenes can interfere with variant detection, and the test may not differentiate variants between PMS2 and PMS2CL. Inherited cancer syndrome caused by different genetic factors cannot be ruled out.
Methodology
NGS (Targeted)
Biomarkers
APC
Gene
LOINC Codes
- 31208-2 - Specimen source
- 94188-0 - APC gene Del+Dup + Full Mut Anl Bld/T
- 56850-1 - Imp & review of lab results
- 62385-0 - Recommendation Patient Doc-Imp
- 55752-0 - Clinical info
- 49549-9 - Ref lab test method
- 75608-0 - Citation Ref Lab Test
- 72486-4 - Lab director name Provider
- 51969-4 - Gene analysis narr rpt Doc
Result Turnaround Time
20-28 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL
Minimum Volume
7 mL
Container
Lavender-top (EDTA) tube or yellow-top (ACD) tube
Collection Instructions
Blood is collected by routine phlebotomy.
Storage Instructions
Room temperature or refrigerated
Causes for Rejection
Frozen specimen; leaking tube; clotted specimen; grossly or hemolyzed specimen; quantity not sufficient for analysis; incorrect anticoagulant.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 60 days |
| Refrigerated | 60 days |
| Frozen | N/A |
Other tests from different labs that may be relevant