VistaSeq® APC Comprehensive Analysis

Casandra

Casandra Test Code LC53568Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 483484CPT Codes 81201, 81203

VistaSeq® APC Comprehensive Analysis

Also known as: Familial Adenomatous Polyposis, Familial Cancer testing, Hereditary Cancer testing, Inherited Cancer testing

Clinical Use

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Use

This assay is intended for patients with a history consistent with Familial Adenomatous Polyposis.

Special Instructions

A hereditary cancer clinical questionnaire should be submitted with all specimens. Contact CMBP genetic services at 800-345-4363 to coordinate testing. To order Oragene Dx 500 saliva collection kits using PeopleSoft No. 87917, contact your local Labcorp branch supply department.

Limitations

Sequencing cannot detect variants in regions not covered by this analysis, including noncoding or deep intronic variants, and may not reliably detect changes in repetitive elements, such as microsatellite repeats. The test may miss mosaic variants, inversions, or other genomic rearrangements like transposable element insertions. Copy number analyses may not detect rearrangements such as translocations or some partial exon rearrangements. Pseudogenes can interfere with variant detection, and the test may not differentiate variants between PMS2 and PMS2CL. Inherited cancer syndrome caused by different genetic factors cannot be ruled out.

Test Details