VistaSeq® Breast and GYN Cancer Panel
Also known as: Familial Cancer testing, Hereditary Cancer testing, Inherited Cancer testing
Use
This assay is intended for patients with a family history consistent with an inherited cancer syndrome.
Special Instructions
Not provided.
Limitations
This test cannot detect variants in regions not covered, such as noncoding or deep intronic variants. It may not reliably identify changes in repetitive elements like microsatellite repeats and may not detect mosaic variants, inversions, or genomic rearrangements like transposable elements. Presence of rare variants under primer sites or homopolymeric regions can affect sequence analysis. It does not determine if heterozygous variants are on the same or different chromosome copies. Presence of pseudogenes, such as PMS2CL, can interfere with gene variant detection. Copy number analyses may not detect certain genomic rearrangements or exact breakpoints.
Methodology
NGS (Targeted)
Biomarkers
LOINC Codes
- 73977-1 - Cancer multigene analysis Bld/T
- 31208-2 - Specimen source
- 51968-6 - Gene dis anl interp-Imp
- 69548-6 - Genetic var assess
- 47042-7 - Counseling note
- 77202-0 - Laboratory comment Report
- 49549-9 - Ref lab test method
- 75608-0 - Citation Ref Lab Test
- 72486-4 - Lab director name Provider
- 51969-4 - Gene analysis narr rpt Doc
Result Turnaround Time
24-28 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL
Minimum Volume
7 mL
Container
Lavender-top (EDTA) tube or yellow-top (ACD) tube
Collection Instructions
Blood is collected by routine phlebotomy.
Storage Instructions
Room temperature
Causes for Rejection
Frozen specimen; leaking tube; clotted specimen; grossly or hemolyzed specimen; quantity not sufficient for analysis; incorrect anticoagulant.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 60 days |
| Refrigerated | 60 days |
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