VistaSeq® GYN Cancer Panel
Also known as: Familial Cancer testing, Hereditary Cancer testing, Inherited Cancer testing
Use
This assay is intended for patients with a family history consistent with an inherited cancer syndrome.
Special Instructions
Not provided.
Limitations
Sequencing cannot detect variants in regions not covered by this analysis, including noncoding or deep intronic variants, and may not reliably detect changes in repetitive elements, such as microsatellite repeats. Sequencing may not detect mosaic variants, inversions, or other genomic rearrangements such as transposable element insertions. Method limitations include complications in PMS2 and PMS2CL analysis, and inability to determine allelic composition of variants. This test does not intend to identify somatic variants or ensure detection of all genomic rearrangements.
Methodology
NGS (Targeted)
Biomarkers
LOINC Codes
- 73977-1 - Cancer multigene analysis Bld/T
- 31208-2 - Specimen source
- 51968-6 - Gene dis anl interp-Imp
- 69548-6 - Genetic var assess
- 47042-7 - Counseling note
- 77202-0 - Laboratory comment Report
- 49549-9 - Ref lab test method
- 75608-0 - Citation Ref Lab Test
- 72486-4 - Lab director name Provider
- 51969-4 - Gene analysis narr rpt Doc
Result Turnaround Time
22-28 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL
Minimum Volume
7 mL
Container
Lavender-top (EDTA) tube or yellow-top (ACD) tube
Collection Instructions
Blood is collected by routine phlebotomy.
Storage Instructions
Room temperature
Causes for Rejection
Frozen specimen; leaking tube; clotted specimen; grossly or hemolyzed specimen; quantity not sufficient for analysis; incorrect anticoagulant.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 60 days |
| Refrigerated | 60 days |
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