VistaSeq® MEN1 Comprehensive Analysis
Also known as: Familial Cancer testing, Hereditary Cancer testing, Hyperparathyroidism, Inherited Cancer testing, MEN1
Use
This assay is intended for patients with a history consistent with Multiple Endocrine Neoplasia, type 1.
Special Instructions
Not provided.
Limitations
Sequencing cannot detect variants in regions not covered by this analysis, including noncoding or deep intronic variants, and may not reliably detect changes in repetitive elements, such as microsatellite repeats. It may also miss mosaic variants, inversions, or other genomic rearrangements such as transposable element insertions. The assay is not intended to detect somatic variants, and bone marrow transplantation may affect the outcome. The presence of pseudogenes can interfere with detecting variants in certain genes, and copy number analyses may not detect certain genomic rearrangements.
Methodology
NGS (Targeted)
Biomarkers
MEN1
Gene
LOINC Codes
- 41089-4 - MEN1 gene Mut Anl Bld/T
- 31208-2 - Specimen source
- 41089-4 - MEN1 gene Mut Anl Bld/T
- 56850-0
- 62385-0 - Recommendation Patient Doc-Imp
- 42349-1
- 49549-9 - Ref lab test method
- 75608-0 - Citation Ref Lab Test
- 72486-4 - Lab director name Provider
- 11502-2 - Laboratory report
Result Turnaround Time
21-24 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL
Minimum Volume
7 mL
Container
Lavender-top (EDTA) tube or yellow-top (ACD) tube
Collection Instructions
Blood is collected by routine phlebotomy.
Storage Instructions
Room temperature or refrigerated
Causes for Rejection
Frozen specimen; leaking tube; clotted specimen; grossly or hemolyzed specimen; quantity not sufficient for analysis; incorrect anticoagulant.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 60 days |
| Refrigerated | 60 days |
| Frozen | N/A |
Other tests from different labs that may be relevant