Vitamin C
Also known as: Ascorbic Acid, C, Vitamin
Use
Along with dietary history, evaluating serum ascorbic acid levels should be considered for patients with classic signs and symptoms of scurvy, as well as for those with common, nonspecific, chronic musculoskeletal complaints. Vitamin C deficiency is generally defined as plasma or serum concentrations less than 0.2 mg/dL, or the the level at which signs and symptoms of scurvy may appear. Serum ascorbic acid concentrations between 0.2 and 0.4 mg/dl are considered low.2,28,29
Special Instructions
Plasma separation and protection from light are vital during sample collection to ensure accurate results. Immediate freezing and storing on dry ice is necessary for stability. Separate specimens are required when multiple tests are ordered.
Limitations
This test was developed by LabCorp and has not been cleared or approved by the FDA. Results can be influenced by improper sample handling, such as not protecting the specimen from light or improper freezing. The presence of anticoagulants other than lithium heparin can lead to sample rejection.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 1903-4
- 1903-4
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
1 mL
Minimum Volume
0.5 mL
Container
Green-top (lithium heparin) tube; amber plastic transport tube with amber-top. If unavailable, cover with aluminum foil.
Collection Instructions
Collect blood into a green-top tube, mix gently. Separate plasma promptly and transfer to an amber plastic tube. Freeze on dry ice within 4 hours.
Storage Instructions
Freeze immediately and protect from light.
Causes for Rejection
Anticoagulants other than lithium heparin; specimen not protected from light
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unstable |
| Refrigerated | Unstable |
| Frozen | 14 days |