11-nor-Delta-9-Tetrahydrocannabinol-9-Carboxylic Acid (Carboxy-THC) Confirmation, Chain of Custody, Meconium
Use
This test is useful for detecting in utero drug exposure to marijuana (tetrahydrocannabinol) up to 5 months before birth. The presence of 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid at a concentration of 5 ng/g or greater is indicative of such exposure. Chain of custody is required whenever results could be used in legal proceedings, ensuring that the specimen was controlled by authorized personnel throughout the process to prevent tampering.
Special Instructions
This test requires chain of custody, meaning the collection, handling, and analysis of the specimen must be documented and controlled to ensure the test results are suitable for court proceedings. Chain-of-custody specimens should be shipped overnight.
Limitations
There is a lack of a dose-response relationship between marijuana usage during pregnancy and the levels found in meconium, making it challenging to determine the exact amount or timing of exposure. The disposition of the drug in meconium is complex and not fully understood, potentially affecting the accuracy of exposure assessment.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 69007-3
- 69007-3
- 69050-3
- 77202-0
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
1 g
Minimum Volume
0.3 g
Container
Chain-of-Custody Meconium Kit (T653)
Collection Instructions
Collect entire random meconium specimen.
Causes for Rejection
Grossly bloody; Diapers; Broken seal
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 21 days |
| Frozen | 28 days |