Acyclovir, Plasma
Use
Therapeutic drug monitoring of acyclovir levels in plasma to assess dosing adequacy; reference ranges include peak (0.40–2.0 mcg/mL) and trough (0.14–1.2 mcg/mL) during chronic oral dosing, and expected acyclovir levels following valacyclovir administration (2.0–4.0 mcg/mL) (peak) ([mayocliniclabs.com](https://www.mayocliniclabs.com/test-catalog/overview/75396?utm_source=openai)).
Special Instructions
Specimens cannot be shared between multiple orders. Lavender top or pink top EDTA tube required; plasma gel/PST are not acceptable. Must centrifuge and aliquot plasma into a plastic vial and send refrigerated. Submission in plastic vial. Performance by NMS Labs ([mayocliniclabs.com](https://www.mayocliniclabs.com/test-catalog/overview/75396?utm_source=openai)).
Limitations
This test was developed and its performance characteristics determined by NMS Labs and has not been cleared or approved by the U.S. Food and Drug Administration ([mayocliniclabs.com](https://www.mayocliniclabs.com/test-catalog/overview/75396?utm_source=openai)).
New York Approved
Methodology
Mass Spectrometry (LC‑MS/MS)
Biomarkers
LOINC Codes
- 9416-9
Result Turnaround Time
9-11 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
1 mL
Minimum Volume
0.5 mL
Container
Lavender top or pink top (EDTA) tube; plasma must be aliquoted into plastic vial
Collection Instructions
Draw blood in EDTA (lavender or pink top) tube; centrifuge and aliquot 1 mL plasma into plastic vial; send refrigerated.
Storage Instructions
Refrigerated (preferred), ambient acceptable, frozen acceptable
Causes for Rejection
Plasma gel/PST tubes not acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 30 days |
| Refrigerated | 30 days |
| Frozen | 120 days |