Adenovirus, Molecular Detection, PCR, Varies
Use
Adenoviruses are known to cause a wide range of diseases such as pneumonia, cystitis, conjunctivitis, diarrhea, hepatitis, myocarditis, and encephalitis across various human organ systems. Infections can occur at any time and in all age groups. Over 50 adenovirus serotypes exist, grouped into six subgenera. Molecular detection through PCR provides a rapid, specific, and sensitive means of diagnosis for adenovirus DNA, bypassing the lengthy culture methods and less sensitive serological tests.
Special Instructions
Submitting a specimen source is mandatory, including the main anatomical site of collection. This requirement aims to ensure proper testing and result interpretation.
Limitations
While a positive result indicates the presence of adenovirus DNA, a negative result does not rule out infection due to possible low levels of viral DNA beyond detection limits. This test is not for screening healthy patients; it's for patients with clinical history and symptoms suggesting adenovirus infection.
Methodology
PCR-based (Real-Time PCR)
Biomarkers
LOINC Codes
- 39528-5
- 31208-2
- 39528-5
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Body Fluid
Volume
0.5 mL
Minimum Volume
0.5 mL
Container
Sterile container
Collection Instructions
Do not centrifuge.
Causes for Rejection
Calcium alginate-tipped swab, Wood swab, Transport swab containing gel, Dry/flocked ESwab
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |
| Frozen | 7 days |
