Adrenal Mass Panel, 24 Hour, Urine
Use
Aiding in assessing malignancy in adrenal masses. May aid in improving diagnostic and prognostic prediction and dissect disease mechanisms, including diagnostic assessment and follow-up of adrenal cortical carcinoma, differential diagnostic assessment of adrenal tumors, and assessment related to Cushing syndrome, mild autonomous cortisol secretion, primary aldosteronism, inborn errors of steroidogenesis, and polycystic ovary syndrome. The test assists in determining whether an adrenal mass is benign or malignant by profiling urinary steroids.
Special Instructions
Collection of urine for a full 24 hours is required, and the total volume must be recorded. For non-electronic orders, the Adrenal Mass Panel Patient Information form is required. Specimens should be shipped frozen. Required information includes age at diagnosis, gender, mode of discovery, tumor diameter, unenhanced CT scan, and hormonal excess. This information must be provided within 5 days of specimen receipt to avoid delays or cancellation.
Limitations
The test should not be used for pediatric patients, and the risk assessments are based on adult populations. Test results cannot be used as absolute evidence for the presence or absence of malignant disease and should not form the sole basis for a diagnosis or treatment decision. It may be difficult to interpret results in pregnant women and in patients with severe liver or kidney function impairment. Risk assignments for other malignancies may not be as accurate as those for adrenal cortical carcinoma or adenoma.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 95556-7
- 63932-8
- 76691-5
- 95557-5
- 21889-1
- 95558-3
- 95559-1
- 13362-9
- 3167-4
- 95787-8
- 95788-6
- 95789-4
- 95790-2
- 95791-0
- 95792-8
- 77202-0
- 6705-8
- 95560-9
- 2268-1
- 95561-7
- 13612-7
- 95562-5
- 95563-3
- 95564-1
- 95565-8
- 95566-6
- 95567-4
- 95568-2
- 95569-0
- 95570-8
- 95571-6
- 95572-4
- 2834-0
- 95573-2
- 95574-0
- 95575-7
- 2836-5
- 95576-5
- 50643-6
- 95577-3
- 2996-7
- 95578-1
- 14158-0
- 95579-9
- 13611-9
- 95580-7
- 2995-9
- 95581-5
- 21044-3
- 95582-3
- 53634-2
- 95583-1
- 6701-7
- 95584-9
- 6700-9
- 95585-6
- 14044-2
- 95586-4
- 16116-6
- 95587-2
- 55906-2
- 95588-0
- 95589-8
- 95590-6
- 40867-4
- 95591-4
- 73884-9
Result Turnaround Time
7-24 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
4 mL
Minimum Volume
2 mL
Container
Plastic urine tube
Collection Instructions
Collect urine for a full 24 hours and record the total volume. Do not add preservatives. Mix entire 24-hour collection well before aliquoting into a 5 mL plastic tube.
Storage Instructions
Ship specimens frozen.
Causes for Rejection
Preserved specimens will be canceled. Gross hemolysis and gross icterus are acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |