Use

The Aldolase, Serum test is useful for the detection of muscle diseases. Aldolase is an enzyme involved in the glycolysis pathway, crucial for muscle energy production. It catalyzes the conversion of fructose 1,6-diphosphate to dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, important for energy generation, especially in muscle tissue. Elevated levels of aldolase can indicate muscle diseases such as Duchenne muscular dystrophy, dermatomyositis, polymyositis, and limb-girdle muscular dystrophy. While creatine kinase levels are more specific, aldolase can also be elevated in patients with myositis who have normal CK values.