Alkaline Phosphatase, Serum
Use
Alkaline phosphatase (ALP) in serum is used to diagnose and monitor treatment of liver, bone, intestinal, and parathyroid diseases. It is important in detecting conditions such as cholestasis, jaundice, Paget disease, hyperparathyroidism, rickets, osteomalacia, fractures, and malignant tumors. Serum ALP is elevated with increased osteoblast activity due to accelerated bone growth, especially in children and teenagers.
Special Instructions
Not provided.
Limitations
ALP values need to be interpreted with caution in pediatrics, as reference values differ for children and adolescents. Improper specimen collection, handling, or inappropriate test selection may lead to diagnostic confusion. Furthermore, interfering substances must be considered, as they might affect the accuracy of results.
FDA ApprovedNew York Approved
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
Alkaline Phosphatase
Analyte
LOINC Codes
- 6768-6 - ALP SerPl-cCnc
- 6768-6 - ALP SerPl-cCnc
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plastic vial
Collection Instructions
Serum gel tubes should be centrifuged within 2 hours of collection. Red-top tubes should also be centrifuged and aliquoted within 2 hours of collection.
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 7 days |
| Frozen | 60 days |