Alpha-1-Acid Glycoprotein
Use
Alpha-1-acid glycoprotein is an acute phase reactant found in a number of conditions. It migrates with the alpha-1 proteins on serum protein electrophoresis. It is used as a marker for inflammation and is evaluated in conditions such as infections, inflammatory diseases, and different types of cancer. The levels of this glycoprotein can provide insights into the presence of acute or chronic inflammatory responses.
Special Instructions
Fasting overnight is preferred but not required for patients undergoing this test. Collection should be done using a red top or serum gel tube, and serum must be centrifuged and aliquoted into a plastic vial before being sent refrigerated. The preparation and collection instructions help ensure sample integrity and accuracy of test results.
Limitations
The test is limited by the potential for sample rejection if received at room temperature, which affects the accuracy of the results. Moreover, while the test measures alpha-1-acid glycoprotein levels, it does not diagnose specific conditions by itself and should be interpreted in conjunction with other clinical findings and tests. Variability in results can occur based on patient condition and sample handling.
New York Approved
Methodology
Immunoassay (Nephelometry)
Biomarkers
LOINC Codes
- 2685-6
- 2685-6
Result Turnaround Time
4-12 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot 1 mL of serum into a plastic vial. Send refrigerated.
Patient Preparation
Fasting: Overnight, preferred but not required
Causes for Rejection
Received room temperature
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |
| Frozen | 90 days |