Anchovy, IgE, Serum

Casandra

Casandra Test Code MC27304Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID ANCHCPT Code 86003

Clinical Use

Use

This test is useful for establishing the diagnosis of an allergy to anchovy by identifying specific IgE antibodies in the serum that react to the allergen. It helps define the allergens responsible for eliciting signs and symptoms and is used to confirm sensitization prior to commencing immunotherapy. Moreover, it aids in investigating the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens, and identifies allergens responsible for allergic responses or anaphylactic episodes. Testing for IgE antibodies can indicate an increased likelihood of allergic diseases compared to other etiologies when the test results are class 1 or greater.

Special Instructions

If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen. The test includes recommendations for handling allergen-related test applications and guidance on exposure settings when allergens occur. It also offers comprehensive insight into the profile of allergic reactions and the allergens predominantly involved.

Limitations

Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in cases where the management does not rely on identifying allergen specificity. Additionally, false-positive results may occur in patients with significantly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases. Interpretations should be made in the context of clinical evaluations, as measurable IgE levels might prevail despite clinically insignificant sensitivity.

Test Details

New York Approved