Anti-TIF-1gamma Antibody
Use
The Anti-TIF-1gamma Antibody test is used in the clinical setting to aid in the diagnosis of certain autoimmune conditions, particularly dermatomyositis. The presence of these antibodies is associated with a heightened risk for malignancy-related myositis. This assay helps confirm suspected autoimmune etiology and guides further investigations for associated conditions such as cancer. A patient's clinical picture, along with this lab result, can assist in forming a comprehensive diagnostic profile.
Special Instructions
Not provided.
Limitations
The test is specific for Anti-TIF-1gamma antibodies, which means it may not detect other antibodies related to dermatomyositis or other autoimmune diseases. False positives and false negatives can occur, and results should be interpreted in the context of the patient's clinical condition and other laboratory findings. Interfering substances such as hemolysis, lipemia, and icterus may affect the accuracy of test results, and specimens with these conditions may be rejected. Additionally, the test has not been cleared or approved by the FDA, limiting its use to laboratory-directed diagnostic interpretation.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
Unknown antibody
Antibody
LOINC Codes
- 96501-2 - TIF1-gamma Ab Ser IA-aCnc
Result Turnaround Time
9-14 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plastic vial
Collection Instructions
Within 1 hour of collection, centrifuge and aliquot 1 mL of serum into a plastic vial. Send refrigerated.
Storage Instructions
Refrigerated 14 days preferred, ambient 7 days, frozen 60 days.
Causes for Rejection
Gross hemolysis, lipemia, icterus, bacterial contamination, and non-serum specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 60 days |