Antidepressant Drug Screen, Qualitative
Use
This test is a qualitative screen for antidepressant drugs in various specimen types. It is designed to detect the presence of tricyclic antidepressants (TCAs) and other related compounds. The test includes analysis for drugs such as Amitriptyline, Clomipramine and Desmethylclomipramine, Cyclobenzaprine, Desipramine, Doxepin and Desmethyldoxepin, Fluoxetine and Norfluoxetine, Imipramine, Maprotiline, Nortriptyline, Paroxetine, Protriptyline, and Sertraline and Desmethylsertraline.
Special Instructions
This test is performed using both Immunoassay (IA) and Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS) methodologies. It is important to note that plasma gel tubes and serum gel tubes are not acceptable for specimen collection.
Limitations
The test is a qualitative analysis and not intended to provide quantitative measures of antidepressant concentrations. It may not detect all possible antidepressants or their metabolites. Cross-reactivity with other medications may result in false-positive results. Interfering substances such as hemolysis, lipemia, or icterus have not been assessed for this assay.
New York Approved
Methodology
Immunoassay (Multiplex Protein Panel)
Biomarkers
LOINC Codes
- 31208-2
Result Turnaround Time
3-9 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
3 mL
Minimum Volume
0.6 mL
Container
Plastic vial
Collection Instructions
Draw blood in a green-top (sodium heparin) tube. Spin down and send refrigerated.
Storage Instructions
Send specimen refrigerated. Stability at room temperature for up to 72 hours, refrigerated for up to 7 days, and frozen for up to 180 days.
Causes for Rejection
Hemolysis, lipemia, icterus.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 7 days |
| Frozen | 180 days |