Antimicrobial Susceptibility, Aerobic Bacteria, Varies
Use
Antimicrobial susceptibility testing determines the minimal inhibitory concentration (MIC) of antimicrobial agents, which is the lowest concentration that inhibits bacterial growth. This test is crucial for identifying suitable antimicrobial therapy for infections caused by aerobic bacteria. It guides clinicians in selecting effective treatments and is particularly important when the susceptibility of the organism cannot be predicted from its identity alone. Clinical breakpoints provided by organizations such as CLSI and EUCAST help in the interpretation of MICs.
Special Instructions
Routine susceptibility testing is performed for all aerobically growing bacteria submitted. The testing identifies the MIC of various antimicrobial agents appropriate to the organism and specimen source. Tests such as the mecA PCR might be added based on initial results. Laboratories need to submit pure cultures with appropriate identification for testing.
Limitations
In vitro results do not guarantee clinical outcome; treatment decisions should not solely rely on test results. Susceptibility testing is viable only with pure culture isolates, and results depend on the precision of the organism's identification and the appropriateness of the specimen collection method. Differences in growth conditions or methodology could affect test results.
New York Approved
Methodology
Culture-based
Biomarkers
LOINC Codes
- 21070-8
Result Turnaround Time
4-7 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
Not provided
Minimum Volume
Not provided
Container
E-Swab collection and transport system
Collection Instructions
Use a flocked swab to obtain a pure cultured isolate sample. Do not submit mixed cultures. Place the swab into the transport system with 1-mL liquid Amies transport medium; if needed, break off the end of the swab and close the transport tube. Ship in the secondary infectious container.
Causes for Rejection
Agar plate samples will be rejected.