Use

The test is useful for diagnosing antithrombin deficiency, whether acquired or congenital. It plays an important role in monitoring the treatment of antithrombin deficiency disorders, including the infusion of antithrombin therapeutic concentrate. Antithrombin deficiency can result in a thrombotic diathesis, making the patient susceptible to venous thromboembolisms such as deep vein thrombosis and pulmonary embolism. It can be due to inherited causes or acquired due to conditions such as liver disease, nephritic syndrome, or chemotherapy, and it has significant implications in heparin therapy resistance.