Arsenic/Creatinine, Ratio, with Reflex, Random, Urine
Use
Preferred screening test for detection of arsenic exposure using random urine specimens. Measurement of urinary total arsenic concentration helps detect recent exposure and when elevated, reflex speciation of arsenic forms (inorganic vs organic) is performed for further risk stratification.
Special Instructions
If total arsenic concentration is 10 mcg/L or greater, then speciation (Arsenic Speciation, Random, U; SPAS) will be performed at additional charge. Patient should avoid seafood for 48 hours prior to collection. If gadolinium- or iodine-containing contrast was administered, delay collection for 96 hours. Refer to Metals Analysis Specimen Collection and Transport for complete instructions.
Limitations
Consumption of seafood prior to collection may lead to misleading elevated arsenic results. This test cannot predict health effects of arsenic exposure. It measures only recent exposure via urinary excretion. All specimens evaluated for suitability; unsuitable specimens may be rejected.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 13463-5
- 2161-8
- 13463-5
- 5586-3
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
6 mL
Minimum Volume
3 mL
Container
Clean, plastic urine container with no metal cap or glued insert; plastic 10‑mL urine tube or clean plastic aliquot container, no metal cap or glued insert
Collection Instructions
Collect a random urine specimen; see Metals Analysis Specimen Collection and Transport for complete instructions
Patient Preparation
Do not eat seafood for 48 h prior to collection; if gadolinium‑ or iodine‑containing contrast administered, delay collection for 96 h
Causes for Rejection
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 28 days |
| Frozen | 28 days |