Aspergillus flavus IgE
Use
The Aspergillus flavus IgE test is a diagnostic tool used to detect specific IgE antibodies to Aspergillus flavus in human serum. It aids in the diagnosis of allergic diseases, including allergic bronchopulmonary aspergillosis (ABPA) and other related conditions caused by hypersensitivity to Aspergillus flavus. Measuring IgE levels can help in assessing the immune response to Aspergillus flavus allergens and guide appropriate management and treatment strategies for affected patients. The test provides valuable information for clinicians to evaluate allergic conditions and tailor patient-specific therapeutic approaches.
Special Instructions
This test is performed using an enzyme immunoassay (EIA) methodology, which is a sensitive technique for detecting specific IgE antibodies. The test is available for New York clients, as it is approved for use in New York State. Specimens should be sent refrigerated to ensure the stability of the serum and accuracy of the test results. The test is performed from Monday through Friday, which should be taken into account when planning specimen collection and shipment.
Limitations
As with any diagnostic tool, this test has limitations. False-positive results may occur in cases of sensitization without actual clinical allergy. The test results should be interpreted in conjunction with clinical findings, patient history, and other laboratory results for an accurate diagnosis. Additionally, the presence of IgE antibodies does not confirm active disease but indicates sensitization to Aspergillus flavus. Cross-reactivity with other allergens can also lead to equivocal or indeterminate results. Proper sample handling and avoidance of grossly hemolyzed, lipemic, or icteric specimens are crucial to ensure test accuracy.
Methodology
Immunoassay (EIA)
Biomarkers
LOINC Codes
- 6024-4
- 6024-4
- 103101-2
Result Turnaround Time
4-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.5 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot 0.5 mL of serum into a plastic vial. Send refrigerated.
Storage Instructions
Refrigerated (preferred) or frozen. Ambient acceptable for up to 28 days.
Causes for Rejection
Gross hemolysis, lipemia, or icterus; mild is acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 28 days |
| Refrigerated | 28 days |
| Frozen | 365 days |
