Beech, IgE, Serum
Use
The test is useful for establishing a diagnosis of an allergy to beech and for defining the allergen responsible for eliciting signs and symptoms. It helps in identifying allergens responsible for allergic response and/or anaphylactic episodes, confirming sensitization prior to immunotherapy, and investigating the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. However, testing for IgE antibodies is not beneficial in patients who have had prior immunotherapy treatment to determine residual clinical sensitivity or where medical management does not require identification of allergen specificity.
Special Instructions
If the test is not ordered electronically, complete and send the Allergen Test Request form (T236) with the specimen.
Limitations
Some individuals with clinically insignificant sensitivity to allergens may still have measurable levels of IgE antibodies, indicating the necessity of interpreting test results within the broader clinical context. Moreover, false-positive results can occur in patients with exceptionally high serum IgE levels (>2500 kU/L) due to nonspecific binding in the assay.
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 6038-4
- 6038-4
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL; For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Preferred: Serum gel; Acceptable: Red top; Submission: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis and gross lipemia are acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
