Bleeding Disorders, Focused Gene Panel, Next-Generation Sequencing, Varies

Use

This test is useful for evaluating hereditary bleeding in patients with a personal or family history suggestive of a hereditary bleeding disorder and initial laboratory testing results indicative of factors VII, VIII, IX, or XI deficiency, or a von Willebrand disease. It helps in confirming a hereditary bleeding disorder diagnosis by identifying known or suspected disease-causing alterations in six genes associated with such disorders. Furthermore, it aids in determining the disease-causing alterations to delineate the molecular defect in a patient with a laboratory diagnosis of a bleeding disorder, facilitates genetic counseling, prognosis, risk assessment, and carrier testing for family members.