Buprenorphine Screen, Random, Urine
Use
Screening for drug abuse or use of buprenorphine. This assay provides a preliminary analytical test result and must be confirmed by a more specific method such as liquid chromatography tandem mass spectrometry when a positive screening result occurs. It is useful in clinical monitoring and management but not intended for employment‐related or forensic testing. Buprenorphine is a partial mu-opioid receptor agonist with reduced clinical effects and prolonged duration; it is metabolized via N-dealkylation to norbuprenorphine, which is active but less potent, and then glucuronidated to inactive forms.
Special Instructions
If ordering electronically, use standard interfaces; otherwise, complete and send a Therapeutics Test Request (T831) with the specimen. For reflex confirmation of positive results, order BUPR (Buprenorphine Screen with Reflex, Random, Urine). For comprehensive opioid screening, order TOSU (Targeted Opioid Screen, Random, Urine). For chain-of-custody testing, order BUPMX. If adulteration suspected or urine creatinine required, order ADULT (Adulterants Survey, Random, Urine). STAT requests are not accepted.
Limitations
As with all immunoassays, false-positive results may occur due to cross-reactivity with substances other than the intended analyte, and false-negative results may occur depending on antibody specificity. Urine dilution, fluid intake, and other biologic factors can influence results. Less than the required 5 mL specimen will compromise the ability to perform necessary testing.
New York Approved
Methodology
Immunoassay
Biomarkers
LOINC Codes
- 93494-3
- 93494-3
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
5 mL
Minimum Volume
Not provided
Container
Plastic urine container (submit in plastic vial); supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Instructions
Collect a random urine specimen; submit 5 mL in one plastic vial; no preservative.
Causes for Rejection
Submitting less than 5 mL will compromise the ability to perform all necessary testing.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |