Cadmium, 24 Hour, Urine
Use
Detects exposure to cadmium, a toxic heavy metal, in 24‑hour urine specimens. Cadmium accumulates in the kidneys and urine levels reflect total body burden, and elevated excretion (>3.0 µg/g creatinine) indicates significant exposure, particularly in occupational settings where OSHA standard is <3.0 µg/g creatinine and BEI is 5.0 µg/g creatinine.
Special Instructions
Patient should avoid seafood for 48 hours before and during collection. Avoid collection if gadolinium or iodine contrast media has been administered in the prior 96 hours. Collect 24‑hour urine, refrigerate within 4 hours of completion. Use a clean plastic container with no metal cap or glued insert. Libraries of PDFs on metals analysis specimen collection and transport are available.
Limitations
Results may be elevated if urine is collected via catheter. High concentrations of gadolinium or iodine (e.g., from contrast media) may interfere with ICP‑MS/MS and specimens should not be collected within 96 hours of administration.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 5612-7
- 5612-7
- 13362-9
- 3167-4
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
3 mL preferred, minimum 1.5 mL
Minimum Volume
1.5 mL
Container
Clean plastic urine container with no metal cap or glued insert; submission: plastic 10‑mL urine tube or clean plastic aliquot container with no metal cap or glued insert
Collection Instructions
Collect urine for 24 hours; refrigerate specimen within 4 hours of completion
Patient Preparation
Do not eat seafood for 48 h prior to and during collection; avoid collection for 96 h after gadolinium or iodine contrast media
Causes for Rejection
All specimens evaluated for test suitability
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 28 days |
| Refrigerated | 28 days |
| Frozen | 28 days |