Cancer-Associated Retinopathy Panel (CARP) by Immunoblot and IHC
Use
The Cancer-Associated Retinopathy Panel (CARP) is used to investigate the presence of antibodies associated with cancer-associated retinopathy. This test involves using immunoblot and immunohistochemistry (IHC) techniques to detect these antibodies, which can be indicative of a paraneoplastic syndrome affecting vision. CARP can be part of a broader diagnostic evaluation for patients presenting with visual symptoms potentially associated with an underlying cancer.
Special Instructions
The test requires submission of a completed OHSU Ocular request form, along with clinical history and referring physician information. This documentation is crucial for processing and completion of the testing.
Limitations
This assay may not detect all possible antibodies associated with cancer-associated retinopathy. Test results should be interpreted in the context of clinical findings and other diagnostic tests. The procedure is limited by the specificity and sensitivity of the immunoblot and IHC methods used.
New York Approved
Methodology
Immunoassay (Immunoblot and IHC)
Biomarkers
Result Turnaround Time
16-35 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
5 mL
Minimum Volume
3 mL
Container
plastic vial
Collection Instructions
Draw blood in a plain, red-top tube(s), serum gel tube(s) is acceptable. Spin down and send 5 mL serum refrigerated in a plastic vial.
Storage Instructions
Refrigerated: 7 days
Causes for Rejection
Hemolysis: Mild reject; Gross reject. Thawing: Warm reject; Cold OK.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |