Carbohydrate Antigen 19-9 (CA 19-9), Pancreatic Cyst Fluid
Use
The Carbohydrate Antigen 19-9 (CA 19-9) test is useful as an adjunct in assessing pancreatic cysts. It is commonly used in conjunction with other tests such as carcinoembryonic antigen (CEA), imaging studies, and cytology. CA 19-9 is a tumor marker that helps in determining whether pancreatic cysts are benign or cancerous.
Special Instructions
This test should not be used as the sole marker for tumor assessment. Additional tests, including CEA and amylase, should be performed alongside this test for a comprehensive evaluation. As a tumor marker, CA 19-9 has limited utility when used alone.
Limitations
CA 19-9 is not specific for pancreatic cancer or malignancy in general. Its utility is limited as a standalone test because serum CA 19-9 may be elevated in non-malignant conditions. Some individuals may not produce CA 19-9 due to being Lewis nonsecretors, leading to false negative results. Additionally, interference from human anti-animal antibodies may occur, which could affect the test outcome.
New York Approved
Methodology
Immunoassay (Immunoenzymatic Assay)
Biomarkers
LOINC Codes
- 97750-4
- 97750-4
- 39111-0
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plain, plastic, screw-top tube
Collection Instructions
For 12 hours prior to specimen collection, the patient should not take any multivitamins or supplements containing biotin. Source specimen should be pancreatic cyst or pseudocyst fluid.
Patient Preparation
Do not take multivitamins or dietary supplements containing biotin (vitamin B7) for 12 hours before specimen collection.
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 7 days |
| Frozen | 90 days |