CD10 Immunostain, Technical Component Only
Use
CD10 is a cell surface glycoprotein present on various cells, including bone marrow B precursors and myeloid cells, follicle center B cells, and more. It is most useful in diagnosing B-precursor-acute lymphoblastic leukemia, Burkitt lymphoma, and lymphomas of follicle cell center origin, such as follicular lymphoma and a subset of large B-cell lymphomas.
Special Instructions
This test includes only technical performance of the stain; no pathologist interpretation is provided. Technical component only stains should not be ordered with PATHC / Pathology Consultation, as they will be canceled if ordered together. Shipping instructions include attaching the appropriate labels to the transport container.
Limitations
Age of a cut paraffin section can affect immunoreactivity, as charges of glass slides might be affected by environmental factors leading to inconsistent staining. Stability thresholds vary and are antigen dependent; best practice is for paraffin sections to be cut within 6 weeks. Poor storage conditions of slides can alter the slide staining results.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Attach the green pathology address label and the pink Immunostain Technical Only label included in the kit to the outside of the transport container.
Storage Instructions
Best practices for storage of positively charged slides include minimizing storage after being unpackaged, limiting exposure to high humidity and heat, and minimizing exposure to plastics.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient (preferred) |