CD273 (PD-L2) Immunostain, Technical Component Only
Use
CD273, also known as programmed cell death 1-ligand 2 (PD-L2), regulates T-cell activation and immune responses. It is a member of the B7 family of cell surface ligands. CD273 (PD-L2) is useful in differentiating primary mediastinal large B cell lymphoma from diffuse large B cell lymphoma.
Special Instructions
This test includes only technical performance of the stain; no pathologist interpretation is provided. Technical component only stains should not be ordered with PATHC / Pathology Consultation. If ordered with PATHC, the stains will be canceled. Attach the green pathology address label and the pink Immunostain Technical Only label to the transport container.
Limitations
The charge of glass slides can be affected by environmental factors and may alter slide staining. Sending unsuitable glass slides can result in inconsistent staining. Best practice suggests that paraffin sections be cut within 6 weeks. Additionally, age of cut sections can affect immunoreactivity. Stability thresholds vary among literature and are antigen-dependent.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- Order only;no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Causes for Rejection
Wet/frozen tissue, Cytology smears, Nonformalin fixed tissue, Nonparaffin embedded tissue, Noncharged slides, ProbeOn slides, Snowcoat slides