CD38 Immunostain, Technical Component Only
Use
CD38 (cluster of differentiation 38) is expressed in a variety of cell types, including hematopoietic precursors, plasma cells, germinal center B cells (weakly), a subset of T and NK cells, erythrocytes, platelets, prostatic epithelium, and smooth and striated muscle cells. Its expression may be useful in the diagnosis of lymphoproliferative and plasma cell proliferative disorders.
Special Instructions
Not provided.
Limitations
This test does not include pathologist interpretation, only technical performance of the stain. Interpretation of this test should be performed in the context of the patient's clinical history and other diagnostic tests by a qualified pathologist. The age of a cut paraffin section can affect immunoreactivity. Stability thresholds vary widely among published literature and are antigen dependent. Best practice is for paraffin sections to be cut within 6 weeks. The charge of glass slides can be affected by environmental factors and subsequently may alter slide staining.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
CD38
Protein
LOINC Codes
- Order only;no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Causes for Rejection
Wet/frozen tissue, Cytology smears, Nonformalin fixed tissue, Nonparaffin embedded tissue, Noncharged slides, ProbeOn slides, Snowcoat slides
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient (preferred) |