CD4 Count for Monitoring, New York, Blood
Use
The test is useful for serial monitoring of CD4 T-cell count in patients who are HIV-positive and for follow-up and diagnostic evaluation of primary cellular immunodeficiencies, including severe combined immunodeficiency. It helps in T-cell immune monitoring following immunosuppressive therapy for transplantation, autoimmunity, and other immunological conditions. It's also used for assessing T-cell immune reconstitution post hematopoietic cell transplantation and early screening of gross quantitative anomalies in T cells in infection or malignancies.
Special Instructions
Not provided.
Limitations
This assay should not be used for diagnosing T-lymphocytic malignancies or evaluation of T-cell lymphocytosis of unknown etiology. Timing and consistency in timing of blood collection is critical when serially monitoring patients for lymphocyte subsets.
New York Approved
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
LOINC Codes
- 65759-3 - T-cell subsets CD4+CD8 pnl Bld
- 8122-4 - CD3 Cells # Bld
- 8123-2 - CD3+CD4+ Cells NFr Bld
- 24467-3 - CD3+CD4+ Cells # Bld
- 14135-8 - CD3+CD8+ Cells # Bld
- 54218-3 - CD3+CD4+ Cells/CD3+CD8+ Cll Bld
- 27071-0 - CD45 Cells # Bld
- 8124-0 - CD3 Cells NFr Bld
- 8101-8 - CD3+CD8+ Cells NFr Bld
- 48767-8 - Annotation comment Imp
- 33193-4 - Viable cells NFr Bld
Result Turnaround Time
3-4 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
3 mL
Minimum Volume
1 mL
Container
Lavender top (EDTA)
Collection Instructions
Send whole blood specimen in original tube. Do not aliquot.
Patient Preparation
For serial monitoring, it is recommended that specimen collection be performed at the same time of day.
Causes for Rejection
Gross hemolysis, Gross lipemia, Sample viability <50%
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |