CD52 Cell Expression Evaluation, Varies
Use
This test is useful for detecting cell-surface antigens on malignant cells that are potential therapeutic antibody targets, specifically CD52. It helps in determining the eligibility of patients for monoclonal antibody therapies and in monitoring response to therapeutic antibodies.
Special Instructions
This test should not be used as a shortened diagnostic panel. For a complete diagnostic B-cell, T-cell, or acute immunophenotyping panel, order LCMS / Leukemia/Lymphoma Immunophenotyping, Flow Cytometry, Varies. This test evaluates CD52 expression only. For CD20 or CD49d expression evaluations, order CEE20 or CEE49 respectively.
Limitations
This evaluation does not perform a complete diagnostic B-cell, T-cell, or acute immunophenotyping panel. In some cases, a limited morphologic evaluation will be performed. Specimens must arrive at the laboratory within 4 days of collection. All specimens will be evaluated for test suitability.
New York Approved
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
LOINC Codes
- 100991-9
- 22637-3
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL
Minimum Volume
3 mL
Container
Yellow top (ACD solution A or B), lavender top (EDTA) or green top (sodium heparin)
Collection Instructions
Label specimen as blood. Send specimen in original tube. Do not aliquot.
Storage Instructions
Specimen must arrive within 4 days of collection. Ambient or refrigerated at 4 days.
Causes for Rejection
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 days |
| Refrigerated | 4 days |