CD68 (KP1) Immunostain, Bone Marrow, Technical Component Only
Use
This test aids in the identification of histiocytic and myeloid lineage cells through immunohistochemical staining. It is useful in assessing the presence of granulocytes, monocytes, and macrophages in bone marrow, which can provide critical insights into various conditions like malignant melanoma, Hodgkin lymphoma, and other mesenchymal neoplasms. It serves as a marker for histiocytic-related analyses by targeting a specific carbohydrate moiety of the CD68 molecule.
Special Instructions
This test is for the technical component only and does not provide pathologists' interpretation. It should not be ordered with PATHC / Pathology Consultation. For proper processing, ensure the use of the Immunostain Technical Only Envelope (T693) and apply the green pathology and pink Immunostain Technical Only labels to the transport container.
Limitations
The CD68 (KP1) Immunostain test does not include pathologist interpretation. The staining can be affected by the age and condition of the paraffin sections, environmental factors influencing glass slide charge, and improper specimen handling. Stability of antigen sites can vary, and consistent staining results require adherence to best practices for slide handling and storage.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- Order only;no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Formalin-fixed, paraffin-embedded tissue block or 2 unstained, positively charged glass slides per test ordered, sections 4-microns thick.
Storage Instructions
Ambient (preferred) or Refrigerated.
Causes for Rejection
Wet/frozen tissue, Cytology smears, Nonformalin fixed tissue, Nonparaffin embedded tissue, Noncharged slides, ProbeOn slides, Snowcoat slides.