Cephalosporium acremonium, IgE, Serum
Use
This test is useful for establishing a diagnosis of an allergy to Cephalosporium acremonium. It is used to define the allergen responsible for eliciting signs and symptoms. The test can help identify allergens responsible for allergic responses and/or anaphylactic episodes. It is also used to confirm sensitization before initiating immunotherapy and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. It is not useful for determining residual clinical sensitivity in patients who have previously received immunotherapy or for patients whose medical management does not rely on allergen specificity identification.
Special Instructions
For a listing of allergens available for testing, refer to the Allergens - Immunoglobulin E (IgE) Antibodies document. If not ordering electronically, the Allergen Test Request form (T236) should be completed, printed, and sent with the specimen. The test is performed Monday through Friday, and reports are typically available the same day or within 1 to 3 days.
Limitations
Some individuals with clinically insignificant sensitivity to allergens may still have measurable levels of IgE antibodies, therefore test results must be interpreted in the clinical context. False-positive results may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding. The test is not appropriate for detecting residual clinical sensitivity in those who have undergone immunotherapy, and may not be informative for those whose clinical management decisions do not depend on identifying specific allergen sensitivities.
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 6066-5
- 6066-5
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL; For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Storage Instructions
Refrigerated (preferred) for 14 days, Frozen for 90 days
Causes for Rejection
Gross hemolysis: OK; Gross lipemia: OK
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
