Chlamydia IgM and IgG Panel, Immunofluorescence, Serum
Use
This test aids in the clinical diagnosis of Chlamydia pneumoniae or Chlamydia psittaci infection, both of which are significant pathogens. Chlamydia pneumoniae is unique for being exclusively a human pathogen and accounts for a notable portion of pneumonia cases in humans. Chlamydia psittaci, on the other hand, is transmitted from infected birds and causes psittacosis, characterized by symptoms such as pneumonia, headache, and hepatosplenomegaly. The test uses immunofluorescence to detect IgM and IgG antibodies specific to these pathogens, thereby providing valuable diagnostic information in suspected cases of infection.
Special Instructions
If not ordering electronically, complete, print, and send an Infectious Disease Serology Test Request form with the specimen. For suspected Chlamydia trachomatis infection, separate nucleic acid amplification tests are recommended for accurate diagnosis due to limited sensitivity and specificity of serologic tests for Chlamydia.
Limitations
This test does not detect antibodies against Chlamydia trachomatis and is not suitable for diagnosing infections caused by this species. Antichlamydial IgG can persist for years, necessitating correlation with clinical history and other data. Early in a primary Chlamydia infection, antibodies might not be detectable; thus, a follow-up specimen may be needed. During primary infection, cross-reactive antibodies among Chlamydia species might occur. The test performance characteristics were determined in compliance with CLIA requirements, but it is not cleared or approved by the FDA.
New York Approved
Methodology
Immunoassay (Other)
Biomarkers
LOINC Codes
- 77166-7
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.6 mL
Minimum Volume
0.3 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial. Preferred collection container is a Serum gel tube; red top tube is also acceptable.
Causes for Rejection
Gross hemolysis, lipemia, icterus, or heat-inactivated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 30 days |
| Frozen | 30 days |