Clonidine (Catapres)
Use
Clonidine (Catapres) level measurement is used to monitor therapeutic drug levels in patients undergoing treatment. The test aids in ensuring the proper dosing regimen and has implications in preventing potential side effects such as sedation, which is associated with serum concentrations greater than 1.5 ng/mL. Monitoring the drug concentration can help manage the therapy's effectiveness while avoiding toxicity, as the toxic concentration has not been firmly established.
Special Instructions
The test requires either plasma or serum specimen types for accurate analysis. Proper collection methods must be adhered to, with specified containers and volumes.
Limitations
Clonidine concentrations can vary greatly in individuals; therefore, results should be interpreted in the context of the patient's clinical condition and concurrent medications. The test should not be used as a standalone tool for clinical decision-making but as part of a comprehensive clinical assessment.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 3495-9
- 3495-9
Result Turnaround Time
5-9 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
5 mL
Minimum Volume
1.2 mL
Container
Plastic vial
Collection Instructions
Draw blood in a green-top (sodium heparin) tube, spin down, send refrigerated.
Causes for Rejection
Plasma gel tube is not acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 7 days |
| Frozen | 180 days |