Cocklebur, IgE, Serum
Use
This test is useful for establishing the diagnosis of an allergy to cocklebur by identifying specific IgE antibodies in the serum. It helps define the allergen responsible for eliciting signs and symptoms of an allergic response, which can include anaphylactic episodes. The test also aids in confirming sensitization prior to starting immunotherapy and investigating the specificity of allergic reactions to various allergens, such as insect venom, drugs, or chemicals.
Special Instructions
Not provided.
Limitations
This IgE antibody test is not useful in patients already treated with immunotherapy to check for residual sensitivity. It is also not suitable for identifying allergen specificity when medical management is not dependent on it. Some individuals with minimal clinical sensitivity might have measurable levels of IgE antibodies, and false positives may occur in patients with very high serum IgE levels due to nonspecific binding.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
IgE Antibodies
Protein
LOINC Codes
- 6077-2 - Cocklebur IgE Qn
- 6077-2 - Cocklebur IgE Qn
Result Turnaround Time
0-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL per 5 allergens
Minimum Volume
0.3 mL for 1 allergen, (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |