Common Reed, IgE, Serum
Use
The test is useful for establishing a diagnosis of an allergy to common reed and for defining the allergen responsible for eliciting signs and symptoms. It is useful for identifying allergens responsible for allergic responses and/or anaphylactic episodes. Additionally, it helps confirm sensitization prior to beginning immunotherapy and investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens.
Special Instructions
The test is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in patients where the management does not depend on allergen specificity identification. The test requires a specimen volume of 0.5 mL for every 5 allergens requested.
Limitations
Some individuals with clinically insignificant sensitivity to allergens may present measurable levels of IgE antibodies, leading to false-positive results. Patients with markedly elevated serum IgE (>2500 kU/L) might also receive false-positive results due to nonspecific binding. Test results must be interpreted in the clinical context considering potential interfering substances.
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 6855-1
- 6855-1
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL per 5 allergens
Minimum Volume
0.3 mL
Container
Serum gel, red top, plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Storage Instructions
Refrigerated is preferred. Can also be stored frozen.
Causes for Rejection
Gross hemolysis is acceptable; gross lipemia is acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
