Copper, 24 Hour, Urine
Use
The Copper, 24 Hour, Urine test is useful for the investigation of Wilson disease and obstructive liver disease. By measuring the concentration of copper in a 24-hour urine sample, this test helps in diagnosing and managing conditions associated with abnormal copper metabolism, particularly Wilson disease, which is characterized by excessive copper accumulation in the body.
Special Instructions
Ensure that the urine collection is complete over a full 24-hour period to guarantee accurate results. Patients must follow all preparation and collection instructions carefully to avoid sample rejection.
Limitations
This test cannot distinguish between different sources of excess copper excretion. Conditions other than Wilson disease, such as cholestasis and some liver diseases, may also cause elevated copper levels in urine. False negatives may occur in cases where the patient does not strictly adhere to the urine collection protocol, or if there is contamination of the specimen.
New York Approved
Methodology
Mass Spectrometry (ICP-MS)
Biomarkers
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Collect urine for a complete 24-hour period following the lab's detailed instructions for home urine collection. Ensure no urine is lost during the collection period.
Causes for Rejection
Improper collection, contamination, and incomplete 24-hour collection