Creatinine, 24 Hour, Urine
Use
Urinary creatinine, in conjunction with serum creatinine, is used to calculate the creatinine clearance, which is a measure of renal function. This test is useful for normalizing urinary analytes to account for variation in urinary concentration. It provides an estimate of the glomerular filtration rate, which is valuable for diagnosing and monitoring renal health and dysfunction.
Special Instructions
This test is not orderable individually but as part of a profile with NMH24 / N-Methylhistamine, 24 Hour, Urine; RB24 / Retinol-Binding Protein, 24 Hour, Urine; A124 / Alpha-1-Microglobulin, 24 Hour, Urine. Temperature control or preservative addition are necessary within 4 hours post-collection.
Limitations
The reliability of 24-hour urinary creatinine determinations depends on accurately collected 24-hour specimens. Variability in results can arise from differences in muscle mass or meat intake. Some substances, including rifampicin, levodopa, and certain therapeutic concentrations, can interfere with accuracy, leading to falsely low or high creatinine results.
New York Approved
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
LOINC Codes
- 65634-8
- 2162-6
- 20624-3
- 13362-9
- 3167-4
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
Not provided
Minimum Volume
1 mL
Collection Instructions
24-hour urine collection required; temperature control or preservative must be applied within 4 hours of completion of collection.
Causes for Rejection
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 30 days |
| Frozen | 30 days |