Creatinine, Random, Urine
Use
This test is useful for the calculation of creatinine clearance, which is a measure of renal function, when used with serum creatinine. It also normalizes urinary analytes by creatinine concentration to account for variations between subjects. Creatinine clearance is a common estimate used for glomerular filtration rate, essential for assessing kidney function and monitoring patients with renal disorders.
Special Instructions
Ensure collection of a random urine specimen using a 10 mL plastic urine tube. No preservatives are required. If not ordering electronically, utilize the appropriate Kidney Transplant or Renal Diagnostics Test Request forms for submissions.
Limitations
The use of a 24-hour specimen is preferred for determining creatinine clearance for precise results. Variability in creatinine excretion can occur due to differences in muscle mass or dietary intake, particularly of cooked meat. Acute shifts in glomerular filtration rate might not be detected until a steady state is reached, affecting the amount of urinary creatinine excreted and reducing the reliability of a single random specimen measurement.
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
LOINC Codes
- 2161-8
- 2161-8
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
6 mL
Minimum Volume
1 mL
Container
Plastic, 10-mL urine tube
Collection Instructions
Collect a random urine specimen. No preservative.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 30 days |
| Frozen | 30 days |
