CXCL13 Immunostain, Technical Component Only
Use
CXCL13 (CXC motif chemokine ligand 13) is useful in the classification of nodal T-cell lymphomas with T-follicular helper (TFH) phenotype, and the diagnosis of follicular dendritic cell sarcoma. Immunohistochemical staining helps to assess the expression of CXCL13, offering insights into specific conditions related to T-cell lymphomas and aiding in the differential diagnosis based on cellular morphology and immunophenotypic profile.
Special Instructions
This test includes only the technical performance of the stain; no pathologist interpretation is provided. It should not be ordered with PATHC / Pathology Consultation, as the technical component stains will be canceled if done so. Attach the green 'Attention Pathology' and pink Immunostain Technical Only labels to the outside of the transport container.
Limitations
The test does not include pathologist interpretation; only technical performance of the stain is offered. Interpretation requires Pathology Consultation for a comprehensive diagnostic evaluation. Age of a cut paraffin section can impact immunoreactivity, and stability thresholds are antigen-dependent. Best practice recommends paraffin sections be cut within 6 weeks to ensure optimal results. Nonformalin fixed tissue or nonparaffin embedded tissues will result in specimen rejection.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Preferred: 2 Unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered; sections 4-microns thick. Acceptable: Formalin-fixed, paraffin-embedded tissue block.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient (preferred) |
| Refrigerated | Refrigerated |